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| Interactions: | Dinoprostone
Adverse Effect: an increased risk of oxytocic toxicity (uterine hyperstimulation) Clinical Management: The concurrent use of dinoprostone with ergonovine is contraindicated. A dosing interval of at least 30 minutes is recommended for the sequential use of oxytocic drugs following the removal of the dinoprostone vaginal insert.
Dopamine
Adverse Effect: gangrene of the extremities Clinical Management: Avoid the concurrent use of dopamine and ergonovine. If coadministration is necessary, monitor for evidence of excessive vasoconstriction (cold, pale skin, pain), especially in the extremities. |
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